This commentary presents the case that the CDC manipulated the data it used as a basis for its opioid prescribing guidelines.
By imposing an arbitrary non-standard constraint and excluding some studies that were included in earlier reports, the CDC created a different interpretation by using a different set of data.
Objectives. A recent US federal review and clinical guideline on opioids for chronic pain asserted that the literature contributes no evidence on efficacy because all trials had “inadequate duration.”
To explore the evidence, we examined durations of studies on opioid, nonopioid drug, and behavioral therapies for chronic pain.
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